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O-Methylbulbocapnine and Dicentrine Suppress LPS-Induced Inflammatory Response by Blocking NF-kappaB and AP-1 Activation through Inhibiting MAPKs and Akt Signaling in RAW264.7 Macrophages.
Yodkeeree S, Ooppachai C, Pompimon W, Limtrakul Dejkriengkraikul P. Yodkeeree S, et al. Biol Pharm Bull. 2018;41(8):1219-1227. doi: 10.1248/bpb.b18-00037. Biol Pharm Bull. 2018. PMID: 30068871 Free article.
The natural aporphine alkaloids including crebanine (CN), O-methylbulbocapnine (OMP), and dicentrine (DC), and protoberberine alkaloids, tetrahydropalmatine (THP) and N-methyl tetrahydropalmatine (NTHP), have been found in Stephania venosa. ...
The natural aporphine alkaloids including crebanine (CN), O-methylbulbocapnine (OMP), and dicentrine (DC), and protoberberine …
Anti-invasion effect of crebanine and O-methylbulbocapnine from Stephania venosa via down-regulated matrix metalloproteinases and urokinase plasminogen activator.
Yodkeeree S, Wongsirisin P, Pompimon W, Limtrakul P. Yodkeeree S, et al. Chem Pharm Bull (Tokyo). 2013;61(11):1156-65. doi: 10.1248/cpb.c13-00584. Epub 2013 Aug 28. Chem Pharm Bull (Tokyo). 2013. PMID: 23985774 Free article.
In this study, we investigated the anti-invasive properties of four alkaloids from S. venosa, crebanine (CN), O-methylbulbocapnine (OMBC), tetrahydropalmatine (THP), and N-methyltetrahydropalmatine (NMTHP), in HT1080 human fibrosacroma cells. ...
In this study, we investigated the anti-invasive properties of four alkaloids from S. venosa, crebanine (CN), O-methylbulbocapnine …
A new alkaloid from the fruit of Nandina domestica Thunb.
Peng CY, Liu JQ, Zhang R, Shu JC. Peng CY, et al. Nat Prod Res. 2014;28(15):1159-64. doi: 10.1080/14786419.2014.921166. Epub 2014 Jun 4. Nat Prod Res. 2014. PMID: 24897106
A new steroidal alkaloid, (20S,22R,24R)-24-ethyl-3-oxocholest-4-en-22-amino, named as nandsterine (1), together with 10 known alkaloids, palmatine (2), O-methylbulbocapnine (3), nantenine (4), dehydronantenine (5), glaucine (6), didehydroglaucine (7), dehydrocorydal …
A new steroidal alkaloid, (20S,22R,24R)-24-ethyl-3-oxocholest-4-en-22-amino, named as nandsterine (1), together with 10 known alkaloids, pal …
Antiplatelet and vasorelaxing actions of some aporphinoids.
Chen KS, Ko FN, Teng CM, Wu YC. Chen KS, et al. Planta Med. 1996 Apr;62(2):133-6. doi: 10.1055/s-2006-957835. Planta Med. 1996. PMID: 8657745
Boldine, (+)-N-methylactinodaphnine, (-)-norannuradhapurine x HBr, xylopine, N-acetyllaurolitsine, N-methyllaurotetanine, actinodaphnine, N-methylnandigerine, O-methylbulbocapnine, and liriodenine showed strong inhibition of arachidonic acid (AA)-induced platelet ag …
Boldine, (+)-N-methylactinodaphnine, (-)-norannuradhapurine x HBr, xylopine, N-acetyllaurolitsine, N-methyllaurotetanine, actinodaphnine, N- …
Bioactive alkaloids from Illigera luzonensis.
Chen KS, Wu YC, Teng CM, Ko FN, Wu TS. Chen KS, et al. J Nat Prod. 1997 Jun;60(6):645-7. doi: 10.1021/np9700735. J Nat Prod. 1997. PMID: 9214740
Using antiplatelet aggregation as a guide to fractionation, seven aporphines, actinodaphnine (1), N-methylactinodaphnine (2), launobine (3), dicentrine (4), O-methylbulbocapnine (5), hernovine (7), and bulbocapnine (9), and two oxoaporphines, dicentrinone (6) and li …
Using antiplatelet aggregation as a guide to fractionation, seven aporphines, actinodaphnine (1), N-methylactinodaphnine (2), launobine (3), …
Alkaloids from Stephania venosa as Chemo-Sensitizers in SKOV3 Ovarian Cancer Cells via Akt/NF-κB Signaling.
Mon MT, Yodkeeree S, Punfa W, Pompimon W, Limtrakul P. Mon MT, et al. Chem Pharm Bull (Tokyo). 2018;66(2):162-169. doi: 10.1248/cpb.c17-00687. Chem Pharm Bull (Tokyo). 2018. PMID: 29386467 Free article.
Crebanine (CN), tetrahydropalmatine (THP), O-methylbulbocapnine (OMBC) and N-methyl tetrahydropalmatine (NMTHP) are isoquinoline derived natural alkaloids isolated from tubers of Stephania venosa. ...
Crebanine (CN), tetrahydropalmatine (THP), O-methylbulbocapnine (OMBC) and N-methyl tetrahydropalmatine (NMTHP) are isoquinoli …
Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit.
Le PM, Srivastava V, Nguyen TT, Pradines B, Madamet M, Mosnier J, Trinh TT, Lee H. Le PM, et al. Phytother Res. 2017 Sep;31(9):1357-1368. doi: 10.1002/ptr.5861. Epub 2017 Jul 13. Phytother Res. 2017. PMID: 28703314
A bioassay-guided fractionation led to the isolation of four aporphine and one tetrahydroprotoberberine alkaloids: dehydrocrebanine 1, tetrahydropalmatine 2, stephanine 3, crebanine 4 and O-methylbulbocapnine 5. The characterization of these compounds was based on M …
A bioassay-guided fractionation led to the isolation of four aporphine and one tetrahydroprotoberberine alkaloids: dehydrocrebanine 1, tetra …
[Chemical constituents from Corydalis yanhusuo].
Hu T, Zhang X, Ma S, Cheng Y, Yao X. Hu T, et al. Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1917-20. Zhongguo Zhong Yao Za Zhi. 2009. PMID: 19894534 Chinese.
RESULT: Nine alkaloids were obtained and determined as 7-formyldidehydroglaucine (1), nantenine (2), (+)-O-methylbulbocapnine (3), d-corydaline (4), tetrahydrocoptisine (5), 8-oxocoptisine (6), palmatine (7), tetrahydropalmatine (8), and dehydrocorydaline (9), respe …
RESULT: Nine alkaloids were obtained and determined as 7-formyldidehydroglaucine (1), nantenine (2), (+)-O-methylbulbocapnine …
Vasorelaxing and antioxidant constituents from Hernandia nymphaeifolia.
Chen JJ, Chang YL, Teng CM, Chen IS. Chen JJ, et al. Planta Med. 2001 Oct;67(7):593-8. doi: 10.1055/s-2001-17348. Planta Med. 2001. PMID: 11582533
Three new alkaloids, (+)-nymphaedaline (1), oxo-O-methylbulbocapnine (2), and (+)-laetine (3), have been isolated from the trunk bark of Hernandia nymphaeifolia. ...
Three new alkaloids, (+)-nymphaedaline (1), oxo-O-methylbulbocapnine (2), and (+)-laetine (3), have been isolated from the tru …